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This study of accessible mucous membrane with special reference to the arrangement of the capillaries was stimulated by Ottfried Müller, who is one of the formulators of the "vasoneurotic diathesis." The mucous membranes of the lips, gums, tongue, rectum, conjunctiva and cervix were observed through a binocular magnifying glass, and careful drawings were made of the capillaries. In a general way, the capillary morphology is the same in the skin and the various mucous membranes. Compared with normal persons, those with the "vasoneurotic diathesis" were found to have more irregular capillary formations throughout, which is considered strong evidence for the constitutional and fundamental nature of this diathesis. That this diathesis predisposes to gastric ulcer has been shown by study of excised pieces of gastric mucosa from patients with ulcers. It is claimed that people with characteristic "vasoneurotic" skin capillaries may be assumed to have similar conditions of the mucous membranes
Die Schleimhäute bei der vasoneurotischen Diathese.. Arch Intern Med (Chic). 1932;49(5):878. doi:10.1001/archinte.1932.00150120168018
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