The insensible perspiration has long been a matter of scientific curiosity, for as far back as 1614 it was the subject of investigation by Sanctorius1 in what were probably among the first quantitative measurements of human metabolism. The number of papers that have dealt with insensible perspiration within the last few years indicates a revival of interest in it, a renewed endeavor to interpret its physiologic significance and an attempt to explore the possibilities of its clinical application. Experiments have shown that most of the loss in weight (85 per cent) of the human body by insensible perspiration is due to the evaporation of water from the respiratory surfaces and from the skin,2 and that within certain limits approximately 25 per cent3 of the total heat lost from the human body is abstracted by the evaporation of water from its surfaces.4 On these facts has been
BENEDICT FG, WARDLAW HSH. SOME FACTORS DETERMINING THE INSENSIBLE PERSPIRATION OF MAN. Arch Intern Med (Chic). 1932;49(6):1019–1031. doi:10.1001/archinte.1932.00150130142012
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