More than ten years ago, Gibson and Howard1 undertook a study of the chemical pathology and metabolism of pernicious anemia. Eleven cases along with four cases of other types of anemia were reported. An experimental diet consisting of fruits, green vegetables, lima beans, egg yolk and liver (100 Gm. or more daily) was employed. This diet induced favorable retention of iron and nitrogen and enhanced the remissions in pernicious anemia; beginning in the fall of 1921 it was prescribed as a routine measure in our service, along with other recognized measures employed to promote hematogenesis. The patients were given specific dietary instruction when discharged. The use of such a diet in the therapy for pernicious anemia was urged in that report.
During the present year, three of our patients who received the liver diet before liver therapy was accepted generally as a specific therapeutic procedure have returned to this
GIBSON RB, FOWLER WM. EFFECTS OF PROLONGED LIVER DIETARY IN PERNICIOUS ANEMIA: CASE REPORTS OF THREE PATIENTS RECEIVING LIVER THERAPY FOR NINE AND A HALF, EIGHT AND SEVEN YEARS, RESPECTIVELY. Arch Intern Med (Chic). 1932;50(1):124–130. doi:10.1001/archinte.1932.00150140131007
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