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This is a periodical published six times a year, containing papers on clinical, biologic and therapeutic subjects. Volume 1, no. 4, 1931, is devoted to the gallbladder. It contains articles entitled as follows: "The Influence of Certain Pharmacodynamic Agents on the Contractility of the Gallbladder," "Biliary Disinfection," "Medication for Relaxing the Gallbladder," "Medical Treatment of Chronic Cholecystitis Without Stone," "Hepato-Biliary Action of Vichy Water Collected at the Spring and Tested by Duodenal Tubage, and "Hydromineral Treatment of Hepatic Insufficiency."
In discussing biliary disinfection, the statement is made that sodium bicarbonate changes the ph of the bile and creates a sterility of the biliary passages, and that hence it is of therapeutic value in cases of chronic hepatitis and cholecystitis. The evidence offered is quite inadequate. The author of the section states that Vichy water is a definite chologogue. This conclusion is based on detailed analyses of bile obtained by
Nutrition. Arch Intern Med (Chic). 1932;50(1):170. doi:10.1001/archinte.1932.00150140177017
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