The influence on the blood urea clearance of the ingestion of carbohydrate in the form of dextrose was studied in six persons. The subjects were normal, except that they were reported to have exhibited glycosuria at some previous time. The sugar tolerance test showed that, in regard to their carbohydrate metabolism, three of the subjects were normal, two showed a diminished tolerance for carbohydrates and one had renal glycosuria. None of these disturbances should influence the function of the kidney, as far as the elimination of urea is concerned. By timing carefully the taking of the specimens of urine and blood, we were able to study the blood urea clearance over shorter and longer periods before and after the ingestion of 100 Gm. of dextrose (table 1).
The urea clearance tests were carried out in the same fashion as those described in the preceding paper of this series,1
BRUGER M, MOSENTHAL HO. UREA CLEARANCE TEST AS AN INDEX OF RENAL FUNCTION: II. THE EFFECT OF INGESTION OF CARBOHYDRATE (DEXTROSE). Arch Intern Med (Chic). 1932;50(3):358–361. doi:10.1001/archinte.1932.00150160009002
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