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Article
February 1933

INFECTIOUS POLYPOID COLITIS

Author Affiliations

NASHVILLE, TENN.

From the Department of Pathology, Vanderbilt University School of Medicine.

Arch Intern Med (Chic). 1933;51(2):236-243. doi:10.1001/archinte.1933.00150210066005
Abstract

The colon is a relatively frequent site for multiple polyps of the mucosa with and without chronic ulceration. The true polyp is composed of hyperplastic glandular mucous membrane projecting into the lumen of the bowel. In the literature are recorded cases of so-called pseudopolyposis lymphatica,1 in which the mucosal projections are caused by underlying hyperplastic lymph follicles, but no cited instance has been found simulating the case to be reported, in which nodular polypoid projections into the colon were caused by a peculiar granulation tissue composed mostly of large mononuclear cells filled with what appears to be a specific infectious micro-organism.2 It has not been possible to cultivate the bacillus associated with the lesion, but it is hoped that a record of the case may lead to an earlier recognition of the disease, so that its bacteriology may be studied with care.

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