In recent years rabies in man has become a rare disease, owing to the improved methods of prophylactic treatment and to laws requiring the registration of all dogs and the quarantining of any suspicious animals. We have observed two cases, one of which developed in spite of the accepted prophylactic treatment. The other was that of a woman, aged 22, who was admitted to the Philadelphia General Hospital on April 5, 1931. The report of this case must of necessity be incomplete, because the patient was in the hospital only eighteen hours and was so desperately ill and so agitated that all efforts had to be centered on treatment. Furthermore, the family refused to permit an autopsy, and the coroner on whom the responsibility ultimately fell did not investigate the case. The history that we obtained is a digest of information received from the patient herself on admission, from her