While bronchial disinfection by intrabronchial lavage with various chemotherapeutic agents would appear to be both possible and safe, as determined by experiments on rabbits, and worthy of clinical trial in the treatment of bronchiectasis and other types of chronic suppurative pneumonitis,1 the results of additional experiments summarized in this paper indicate that local immunization and disinfection of the bronchi by intrabronchial injections of vaccines, antivirus and bacteriophage may offer even greater therapeutic possibilities and prove worthy of clinical trial in the treatment of bronchiectasis and other types of pulmonary suppuration.
Undoubtedly subcutaneous and intracutaneous injections of properly prepared autogenous vaccines are sometimes of therapeutic value in certain cases of chronic bronchitis, especially those associated with allergic asthma, but vaccine therapy has generally failed to be of any particular value in the treatment of bronchiectasis.
It would appear that intrabronchial injections of vaccines and antivirus may open up a new and