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Article
July 1933

TREATMENT OF NEUROSYPHILIS: REVIEW OF RESULTS IN SIX HUNDRED AND EIGHTY PATIENTS

Author Affiliations

BALTIMORE

From the Syphilis Division of the Medical Clinic, the Johns Hopkins Hospital.

Arch Intern Med (Chic). 1933;52(1):66-75. doi:10.1001/archinte.1933.00160010073007
Abstract

Since the analyses of the results of treatment of patients with neurosyphilis by Stokes and Osborne (1921),1 Fordyce (1924),2 Stokes and Shaffer (1924)3 and Moore (1927),4 no similar studies dealing with large numbers of cases have been published. The accumulation of further experience with modern methods of treatment permits a report of the results obtained among 1,200 patients treated in the syphilis division of the medical clinic of the Johns Hopkins Hospital.

The clinical material on which the study is based is presented in table 1. All patients are included who on admission presented evidence of neurosyphilis or in whom it subsequently developed. The whole group of 1,199 patients was used for an estimation of the effect of previous inadequate treatment on the period of incubation of clinical neurosyphilis; the results of this study have been published.5

Following the practice of Head and Fearnsides,6 Stokes and

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