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November 1933


Author Affiliations


From the Joslin Diabetic Unit, New England Deaconess Hospital.

Arch Intern Med (Chic). 1933;52(5):664-684. doi:10.1001/archinte.1933.00160050017002

INCIDENCE  Extreme rarity of the coexistence of diabetes mellitus and epilepsy apparently has been accepted as a fact. According to Talbot (1930), "Study of the literature has so far failed to reveal a single report of the coincidence of idiopathic epilepsy and true diabetes mellitus." Trumper (1930) maintained that the theoretical incidence of epilepsy in persons with diabetes should be extremely small because of the ketosis and dehydration which are so constantly associated with diabetes and which are so antagonistic to epilepsy. Joslin (1928), writing about epilepsy, stated, "No clear cut case can be found among my 6,000 glycosurias of whom 5,086 are true diabetics." He did, however, mention several possible cases of epilepsy. Subsequent study of Joslin's diabetic patients furnishes the material for the present report.Bolduan (1932) stated that 2.5 per cent of all deaths in New York City in 1931 were due to diabetes; and Weeks and

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