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December 1933


Arch Intern Med (Chic). 1933;52(6):992. doi:10.1001/archinte.1933.00160060166019

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The growing interest in hypoglycemia is manifested by this comprehensive monograph which contains information drawn from more than five hundred sources. Since the commonest experience with hypoglycemia has followed insulin therapy, most of the publications have appeared since 1922. The condition was noted, however, under certain circumstances long before. It is recalled that nervous symptoms accompanying depression of the blood sugar which occurred after the adminsitration of phlorhizin were described by Fischler in 1913 as "intoxicatio glykopriva." This term, or "glycopenic complex," now suggested by Sigwald, seems to be appropriate in describing the hypoglycemic syndrome; the latter term fixes attention on the change in the blood, yet the symptoms of deficiency of dextrose do not always parallel the changes in blood sugar.

The clinical signs and symptoms are discussed exhaustively, and special attention is given to the various nervous manifestations. It is pointed out that the picture may be identical

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