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This book is composed of material which, for the most part, has appeared under the name of the authors at various times between 1917 and 1927. The causative organism was first described by Whitmore in 1913 and named Bacillus pseudomallei, on account of its similarity to the organism of glanders and because the disease caused by this organism in human beings resembled human glanders. Eighty-three cases have been reported, most of which have occurred in Burma and Malaya. Only two patients have survived. The symptoms of the disease and the pathologic changes are indistinguishable from those in glanders. The organism differs from Bacillus mallei in that it is motile and usually forms a wrinkled growth on glycerin agar. The authors have described an epidemic among laboratory animals (rabbits, guinea-pigs and rats) in Kuala Lumpur probably caused by food that had been contaminated by wild rodents, which are presumably the reservoir