The etiologic diagnosis of arthritis frequently presents many difficulties, and in many cases the cause remains obscure. For that reason, every effort should be made to obtain as much information as possible from the study of the course of the disease and the characteristics of the synovial fluid. During the past two years, we have studied a hundred and twenty samples of synovial fluids from ninety patients with various types of arthritis. We were interested in determining what information of diagnostic value could be obtained from the study of synovial fluid. The types of cases studied are listed in table 1.
All the patients were studied while residing in the hospital. With a needle and syringe, fluid was aspirated from the joints, the usual aseptic precautions being taken. The skin was anesthetized with a 2 per cent solution of procaine hydrochloride.A sample of the aspirated fluid was mixed
KEEFER CS, MYERS WK, HOLMES WF. CHARACTERISTICS OF THE SYNOVIAL FLUID IN VARIOUS TYPES OF ARTHRITIS: STUDY OF NINETY CASES. Arch Intern Med (Chic). 1934;54(6):872–887. doi:10.1001/archinte.1934.00160180046004
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