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Departing from the conventional approach in the didactics of histology, Cowdry builds up the subject with the vascular system as a central theme. The first chapter is devoted to an introductory consideration of the body fluids—tissue fluid, blood and lymph—touching on the physiologic import of these mediums. Cowdry then proceeds with a detailed discussion of blood (sixty-three pages), followed by separate chapters on the blood vessels and the heart, the whole being emphasized as a "principal integrator" system. Lymphatic vessels and the chief lymphoid organs are next considered, with a view to their functional relationships with this integrator system; the endocrines are next discussed as agents of "chemical integration." The digestive system is likewise alined with the vascular mechanism, as a provision for the "intake of water, nutriment, accessory food factors and removal of waste." The respiratory system is as naturally emphasized for its rôle in "oxygen consumption and carbon
A Textbook of Histology: Functional Significance of Cells and Intercellular Substances. Arch Intern Med (Chic). 1935;55(1):169. doi:10.1001/archinte.1935.00160190172015
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