Intestinal intolerance of carbohydrate with symptoms centering around marked meteorism is a rather common condition, the significance of which is often not appreciated. This symptom complex was first described by Schmidt and Strasburger1 in 1901 in Germany and by Herter2 in 1907 in this country. In the recent English medical literature the only publications on this subject have been by Kendall3 and Hurst and Knott.4 Textbooks usually ignore this condition.
In our gastro-intestinal clinic, during the past five years, in 9 per cent of the cases the major diagnosis was intestinal intolerance of carbohydrate. This figure exaggerates the frequency of the condition among patients with conditions related to the digestive tract, as a disproportionately large number of patients with obscure conditions are referred to this clinic for diagnosis, but it indicates that this syndrome is fairly common. From a survey of fifty consecutive cases we find
T. L. ALTHAUSEN, J. B. GUNNISON, M. S. MARSHALL, S. J. SHIPMAN. CARBOHYDRATE INTOLERANCE AND INTESTINAL FLORAI. A CLINICAL STUDY BASED ON SIXTY CASES. Arch Intern Med (Chic). 1935;56(6):1263–1286. doi:10.1001/archinte.1935.00170040197011