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Coming from the pen of an eminent investigator in the field of endocrinology, this book could hardly fail to be of great interest. It is, in fact, a scholarly work dealing with the subject from the fundamentals up. The clinical descriptions are excellent and the illustrations well chosen. In view of all this, one is disappointed by the inadequate way in which certain phases are handled, especially therapy. The question of the use of iodine in cases of exophthalmic goiter is dealt with vaguely, and one is aghast at the directions given for the use of thyroid substance in myxedema. Even more surprising is the suggestion that parathormone be used in osteitis fibrosa cystica, and that in the discussion of the treatment of Addison's disease the use of sodium chloride is passed by with a casual sentence. The discussion of obesity is so confused as to be useless, and emphasis