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Article
March 1936

PNEUMOTHORAX THERAPY IN EXPERIMENTAL LOBAR PNEUMONIA IN THE DOGWITH A REPORT OF A CASE IN MAN

Arch Intern Med (Chic). 1936;57(3):610-629. doi:10.1001/archinte.1936.00170070135012
Abstract

The treatment of lobar pneumonia, both experimental and clinical, with artificial pneumothorax has lately been revived with enthusiasm. The present studies were undertaken to see whether we could corroborate the success reported with the use of pneumothorax in the treatment of experimental lobar pneumonia in the dog.

EXPERIMENTAL PROCEDURE  Healthy dogs weighing from 8 to 12 Kg. were used.

Pneumococcus.  —The method first devised by Coryllos and Birnbaum1 was used. From 20 to 30 cc. of an eighteen to twenty-two hour broth culture of Pneumococcus type I, II or III was centrifugated, and the sediment was suspended in 1 cc. of the supernatant broth. The suspension was then sprayed by gentle air pressure through a 2 mm. brass tube over the mouth of the bronchus of the lower lobe. The bronchoscope was used to locate the bronchus. In some cases the sediment was suspended in liquefied 1.5 per cent

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