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Article
August 1936

EFFECT OF ALKALINE THERAPY FOR PEPTIC ULCER ON UTILIZATION OF DIETARY IRON IN THE REGENERATION OF HEMOGLOBIN

Author Affiliations

SAN FRANCISCO

From the Division of Medicine, University of California Medical School.

Arch Intern Med (Chic). 1936;58(2):278-284. doi:10.1001/archinte.1936.00170120094007
Abstract

Loss of blood over a long period leads to hypochromic anemia, which may properly be attributed to depletion of the iron stored in the body. Regeneration of hemoglobin in patients with uncomplicated anemia of this type occurs after cessation of the hemorrhage with the aid of appropriate iron therapy. One of the frequent causes of this type of anemia is prolonged or recurrent loss of blood from a peptic ulcer. In patients with depletion of stored iron due to a bleeding ulcer, dietary iron alone is insufficient to stimulate rapid formation of hemoglobin, and chronic anemia often persists after the bleeding is stopped.

A common method of treating peptic ulcer is the modified Sippy regimen. This requires the use of large amounts of alkaline powders daily over a long period. Such treatment obviously renders alkaline the contents of the upper part of the gastro-intestinal tract. In recent years it has

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