DISORDERS OF FAT METABOLISM
—Drs. Thannhauser and Magendantz1 have given me permission to include in this section the following review of a paper of theirs to be published in the near future. Dr. Thannhauser and his associates are recognized as outstanding authorites on cholesterol metabolism, a subject which only recently, and to a great extent through their efforts, has become somewhat understandable. It now is well established that the nucleus of the sterols can be manufactured in the body, although it remains not definitely known in what cells or organs this synthesis is accomplished. It is suspected that it is accomplished in the liver; at least the value for cholesterol in the blood is lowered by hepatectomy. Nor is there knowledge as yet as to what raw material serves as the source of the sterol skeleton, other than that certain yeasts are able to make ergosterol from
WILDER RM, WILBUR DL. DISEASES OF METABOLISM AND NUTRITION: REVIEW OF CERTAIN RECENT CONTRIBUTIONS. Arch Intern Med (Chic). 1938;61(2):297–365. doi:10.1001/archinte.1938.00180080139009
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