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Article
April 1938

ASSOCIATION OF HYPERTHYROIDISM WITH PULMONARY TUBERCULOSIS: A REVIEW OF THE LITERATURE AND REPORT OF TWENTY-THREE CASES

Author Affiliations

PHILADELPHIA

From the Sections on endocrine and thoracic disorders of the Medical Clinic, the Hospital of the University of Pennsylvania.

Arch Intern Med (Chic). 1938;61(4):631-645. doi:10.1001/archinte.1938.00180090111008
Abstract

The relation of the thyroid gland to tuberculosis has received much attention in the literature since about the middle of the last century. Clinical, experimental and pathologic observations have produced a diversity of opinions concerning this relation. It is our purpose to review briefly the more important views expressed in the literature and to present clinical observations on the progress of 23 patients with coexistent hyperthyroidism and pulmonary tuberculosis.

REVIEW OF THE LITERATURE  Earlier writers (Virchow, Rokitansky and Hamburger1) believed an antagonism exists between tuberculosis and the thyroid gland and that the latter is immune to invasion. Infections of various types may produce diffuse temporary swelling of the thyroid and congestion or colloid goiter. This seems to be particularly true in cases of tuberculosis, in which parenchymatous or colloid goiter is relatively common.2 Such a goiter may recede as the tuberculosis heals, but if the tuberculosis progresses there

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