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May 1938

The Avitaminoses. The Chemical, Clinical and Pathological Aspects of the Vitamin Deficiency Diseases.

Arch Intern Med (Chic). 1938;61(5):843. doi:10.1001/archinte.1938.00180100153015

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This book is described as a derivation from "The Vitamine Manual," which was written by the senior author fifteen years ago. It is divided into two parts. Part 1 considers the vitamins and the avitaminoses. It deals with the nature and functions of the important vitamins, together with the clinical aspects and anatomic manifestations of their deficiency. Part 2 is devoted to methods of assaying sources of vitamins, clinical tests of the deficiencies and a table of the vitamin values of foods.

The chapters on vitamin A bring together much new information. The two mechanisms of the production of ocular changes are clearly outlined, and the development of the widespread lesions of vitamin A deficiency are explained. The chapters on the subclinical forms of avitaminosis A, B and C are particularly important in that they emphasize the little known fact that mild deficiencies are prevalent and may produce only nonspecific

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