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This book represents a review of the literature on the biology of the pneumococcus resulting from the studies on pneumonia carried out by the Massachusetts Department of Public Health during the years 1931 to 1935 under a grant from the Commonwealth Fund. It comprises a sorting out and evaluation of the literature of the past fifty years. The first chapter is appropriately historical and in the sixteen subsequent chapters is followed by a detailed and orderly analysis of the present knowledge of the pneumococcus. Discussion of morphology, cultural methods and peculiarities, biochemical features, classification, dissociation and related phenomena, pathogenicity for animals and man, chemical constituents, polysaccharide-splitting enzymes, antigenicity and antibodies, immunity, vaccines, chemotherapy and serum treatment lead to a final chapter on unsolved problems. An appendix on special methods includes facts relating to mediums, isolation of the pneumococcus, type determination, preparation of polysaccharides and bacterial enzymes, serologic reactions, potency and
The Biology of Pneumococcus.. Arch Intern Med (Chic). 1939;63(1):199–200. doi:10.1001/archinte.1939.00180180209018
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