Innumerable therapeutic agents have been advocated for the treatment of idiopathic ulcerative colitis. None of them has proved satisfactory, and few have proved of the slightest benefit. The oral administration of liver extract has been tried in the past, apparently with the usual lack of success.1 It was not mentioned by Bargen or by those physicians discussing his most recent report on the therapy of ulcerative colitis,2 nor was it mentioned in his report on the treatment of the anemia which commonly accompanies this disease.3 Buie4 in his recent textbook on proctology did not mention the use of liver in the treatment of ulcerative colitis. As a new form of highly concentrated liver extract for parenteral use is now available, this has been tried in the treatment of 8 patients with colitis, 7 of whom presented classic examples of the ulcerative type of unknown cause. Gratifying
CHENEY G. INJECTIONS OF HIGHLY CONCENTRATED LIVER EXTRACT IN TREATMENT OF IDIOPATHIC ULCERATIVE COLITIS. Arch Intern Med (Chic). 1939;63(5):813–829. doi:10.1001/archinte.1939.00180220003001
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