In the first article of this series a simple method was described for the quantitative determination of urobilinogen in stool and urine. This method is applicable to the analysis either of single specimens of urine and stool or of specimens collected over twenty-four or more hours.
The remarkable investigations of Watson1 constitute the most outstanding contribution to the knowledge of the daily excretion of urobilinogen in health and disease. It is his belief that examination of single specimens of urine and stool is of little aid in diagnosis and that the potential clinical value of studies on urobilinogen can be realized only by determination of the total daily excretion of urobilinogen in stool and urine. The procedure which he employs involves the collection of one or more twenty-four hour specimens of urine and of entire specimens of stool for at least four days.
The clinical value of any type
SPARKMAN R. STUDIES OF UROBILINOGENII. NORMAL VALUES FOR EXCRETION OF UROBILINOGEN IN SINGLE SPECIMENS OF URINE AND STOOL. Arch Intern Med (Chic). 1939;63(5):867–871. doi:10.1001/archinte.1939.00180220057005
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