Disseminated lupus erythematosus is a distinctive cutaneous eruption forming part of a systemic disorder that usually includes also characteristic clinical and anatomic evidences of visceral damage. It is now believed that this disorder may occur without its cutaneous manifestation. There exists a considerable body of literature, chiefly dermatologic, in which the clinical aspects of the disease have been well depicted. Though this literature extends back almost seventy years, it is only within the last fifteen years that the present concept of the disease has been evolved and that the visceral lesions observable in most cases have been accurately described.
The chronic forms of lupus erythematosus, whose relation to the disease under discussion has not yet been fully evaluated, have been known since the early part of the last century as localized cutaneous conditions. However, on the basis of the original observations of Kaposi,1 it has become apparent that with
GINZLER AM, FOX TT. DISSEMINATED LUPUS ERYTHEMATOSUS: A CUTANEOUS MANIFESTATION OF A SYSTEMIC DISEASE (LIBMAN-SACKS): REPORT OF A CASE. Arch Intern Med (Chic). 1940;65(1):26–50. doi:10.1001/archinte.1940.00190070036003
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