The heart is but rarely the site of a primary neoplasm, and it seldom becomes involved by metastatic malignant tumors. It is therefore of unusual interest to both clinicians and pathologists when a tumor involving this structure is discovered. Lymburner,1 in a review of 8,550 necropsies, found 4 cases of primary tumor of the heart and 52 cases of secondary metastatic lesions of the heart. In a review of the literature,2 he found reports of 226 instances of primary cardiac tumors. In a review of the subject in 1931, Yater3 found records of 46 instances of primary sarcoma of the heart. Additional cases have been reported by Morris,4 Barnes and his associates,5 Boman6 and Willius7 and from the Massachusetts General Hospital.8 Only 11 of these were cases of primary sarcoma of the pericardium.
The majority of primary tumors of the heart are benign. About 25 per cent are malignant. The
PARKER RL, BAGGENSTOSS AH, DRY TJ. PRIMARY SARCOMA OF THE PERICARDIUM: REPORT OF A CASE. Arch Intern Med (Chic). 1940;65(1):51–59. doi:10.1001/archinte.1940.00190070061004
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