A survey of the literature on cardiovascular disease for the year 1939 reveals much that is of interest and importance. The most notable contributions are in regard to congenital heart disease, essential hypertension and the treatment of subacute bacterial endocarditis. Consequently, these subjects have been reviewed in considerable detail.
It has long been known that an electrocardiogram similar to that for the adult can be obtained for the embryo at a very early age. With the improvement in amplifying apparatus, electrocardiographic features regarded as characteristic of adults have become recognizable in the electrocardiograms of progressively younger embryos. The studies carried out by Hoff and his associates 1 are interesting in that these investigators were able to secure records from the time that the heart beat of the chick embryo was just commencing through the period of rapid anatomic change leading to the establishment of the fundamental regional divisions
GRAYBIEL A. DISEASES OF THE HEART: A REVIEW OF SIGNIFICANT CONTRIBUTIONS MADE DURING 1939. Arch Intern Med (Chic). 1940;65(5):1053–1082. doi:10.1001/archinte.1940.00190110182011
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