Paroxysmal hypertension due to an adrenal medullary tumor may progress so far as to cause death from irreparable vascular damage, or death may ensue from other causes. The disease can be diagnosed in its early stages and eradicated by surgical intervention. There are excellent reviews of the literature by Belt and Powell,1 Wells and Boman,2 Nuzum and Walton,3 Edward,4 Lazarus and Eisenberg5 and Coller, Field and Durant.6 Although there have been many valuable case reports, including those of the authors just mentioned as well as those of Beer, King and Prinzmetal,7 Evans,8 Holst,9 Binger and Craig,10 Brunschwig, Humphreys and Roome,11 Kremer,12 Kelly, Piper, Wilder and Walters,13 MacKenzie and McEachern,14 and Palmer and Castleman,15 together with those in the foreign literature, the clinical features of the disease have not been duly stressed. It is for this reason that we are reporting 2 cases of paroxysmal hypertension and emphasizing the manifestations.
VAN EPPS EF, HYNDMAN OR, GREENE JA. CLINICAL MANIFESTATIONS OF PAROXYSMAL HYPERTENSION ASSOCIATED WITH PHEOCHROMOCYTOMA OF ADRENAL: REPORT OF A PROVED AND OF A DOUBTFUL CASE. Arch Intern Med (Chic). 1940;65(6):1123–1129. doi:10.1001/archinte.1940.00190120040004
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