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Article
September 1940

DIABETES INSIPIDUS ASSOCIATED WITH DIABETES MELLITUSMETABOLIC STUDIES AND REPORT OF A CASE

Arch Intern Med (Chic). 1940;66(3):607-624. doi:10.1001/archinte.1940.00190150078006
Abstract

The development of glycosuria in a patient with diabetes insipidus is not unique and frequently accompanies this metabolic disorder.1 The coexistence of frank diabetes mellitus and diabetes insipidus, on the other hand, is rare, and less than 25 case reports on patients with both dyscrasias2 have been recorded in the available literature. Overlapping of signs and symptoms and the possible existence of at least two types of each disease have rendered the confirmation of both diagnoses difficult. Recent advances in the technic of study and interpretation of metabolic disorders have been of great help, however, and it is believed that the data to be presented satisfy the criteria for the diagnosis of diabetes insipidus and of diabetes mellitus. The patient who will be discussed in this communication was under observation intermittently for more than eighteen months. On three occasions during this time she was admitted for observation to

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