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September 1940


Author Affiliations

Instructor in Internal Medicine, University of Cincinnati, and Director of the Diabetic Clinic, Cincinnati General Hospital; Fellow in Diabetes, Department of Internal Medicine, University of Cincinnati, and Clinician in the Diabetic Clinic, Cincinnati General Hospital; Research Dietitian, Department of Internal Medicine and Laboratory for Experimental Medicine, University of Cincinnati CINCINNATI

Arch Intern Med (Chic). 1940;66(3):679-687. doi:10.1001/archinte.1940.00190150150011

Several investigators have published results indicating a definite value of vitamin therapy for diabetes.1 Careful survey of their publications, however, reveals lack of a proper period of control of diabetes before institution of the therapeutic tests. In few of the case histories described are there evidences of stability in the diabetic state before the special therapy was initiated. Thus it is always doubtful whether the improvement observed was due to the vitamins given or to the continued regulation of dietary and insulin needs. Diabetic patients were often given vitamin preparations while they were still improving under previously instituted dietary and insulin regimens, and any further improvement was credited to the vitamin.

Good results have been claimed for administration of thiamine and ascorbic acid to diabetic persons, even though most diabetic diets are adequate in these two substances. Since these claims seem to have been based in most instances on

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