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January 1941


Author Affiliations


From the Department of Internal Medicine, University of Virginia Hospital.

Arch Intern Med (Chic). 1941;67(1):43-71. doi:10.1001/archinte.1941.00200010053004

The pleuropulmonary lesions associated with tularemia present such characteristic morphologic features that they must be accepted as a manifestation rather than a complication of the disease. These pathologic changes are frequent in persons with tularemia, and a variety of thoracic conditions may result clinically on account of their peculiar nature. These abnormalities in the chest may even obscure, and prevent the diagnosis of, the underlying tularemia. It is the purpose of this presentation (a) to review the salient morbid anatomic and pathophysiologic features of pleuropulmonary tularemia and (b) to analyze the clinical observations in a group of 95 unselected cases of tularemia with particular reference to abnormalities in the chest.

REVIEW OF PATHOLOGIC CHANGES  Because of duplications in the literature it is difficult to state exactly the number of reported cases of tularemia in which necropsy was done. Foshay1 collected 43 necropsy reports but apparently failed to include 10

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