Kraus and Nicolai (1910),1 owing to the results of experiments with animals, were led to believe that extrasystoles with positive deflection in the right auricle-apex lead were provoked by excitation of a zone of the heart base corresponding to the right ventricle (extrasystole type B = base); that extrasystoles with a negative deflection were due to excitations of the apex (extrasystole type A = apex), and that those with a configuration in "M" were provoked by excitations of the middle portion of the septum (extrasystole type C = central). Kahn (1910),2 Rothberger and Winterberg (1913),3 Lewis (1916)4 and Padilla (1924)5 have proved that the divers forms of extrasystolic complexes are representative not solely of the spot stimulated but also of the ventricle that receives the stimulus. According to the results of that research, extrasystoles with a negative deflection in lead I start in the left ventricle, and those
CASTEX MR, BATTRO A, GONZÁLEZ R. DIAGNOSIS OF THE SITE OF ORIGIN OF VENTRICULAR EXTRASYSTOLES IN HUMAN BEINGS. Arch Intern Med (Chic). 1941;67(1):76–90. doi:10.1001/archinte.1941.00200010086006
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