Although a large number of spirochetal diseases have been described, in only a few have the causative organisms been cultured from the blood. Larson and Barron1 observed a patient with Vincent's stomatitis and osteomyelitis who died after seven weeks of a severe febrile illness. Two days before death a sample of the patient's blood was cultured on ascitic agar in a Novy anaerobic jar at 37 C. After a few days fusiform bacilli appeared in the culture. Attempts were made to subculture these organisms on plain agar, ascitic broth, plain broth, ascitic agar and Löffler's blood serum. No aerobic growth was observed. Growth occurred in all of the anaerobic cultures except the one containing plain agar only. Optimum growth occurred on ascitic agar. When horse blood agar was used some of the organisms exhibited a few spirals. Larson and Barron expressed the belief that the spiral organisms were modified
WILLIAMS RH. FUSOSPIROCHETOSIS: RECOVERY OF THE CAUSATIVE ORGANISMS FROM THE BLOOD, WITH REPORT OF TWO CASES. Arch Intern Med (Chic). 1941;68(1):80–93. doi:10.1001/archinte.1941.00200070090005
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