The purpose of this paper is to present a case of clinical lipoid nephrosis which was studied over a period of four years and finally at autopsy. Nephritis with associated uremia developed terminally, and autopsy revealed the anatomic changes characteristic of chronic glomerulonephritis.
A brief statement regarding the controversies relating to the nature of lipoid nephrosis may be presented to clarify the issues involved in this case.
One group of workers1 has expressed the belief that lipoid nephrosis is a separate clinical and pathologic entity distinct from chronic glomerulonephritis. Many of this group contended that patients with "pure" lipoid nephrosis will either recover from this disease or die of an intercurrent infection. They also have stated that the diagnosis of lipoid nephrosis is excluded even by the infrequent finding of a few red cells in the urine, slight elevations of blood pressure or a slight rise in blood nonprotein
GILBERT GG. CLINICAL LIPOID NEPHROSIS: WITH SPECIAL REFERENCE TO ITS TRANSFORMATION INTO CLINICAL AND PATHOLOGIC CHRONIC GLOMERULONEPHRITIS. Arch Intern Med (Chic). 1941;68(3):591–598. doi:10.1001/archinte.1941.00200090218010
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