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Article
April 1942

LIVER AND BILIARY TRACT: A REVIEW FOR 1941

Author Affiliations

NEW YORK

From the Clinic for the Study of Disease of the Liver and Biliary Tract of the Department of Medicine and the Department of Surgery, New York Post-Graduate Medical School and Hospital, Columbia University.

Arch Intern Med (Chic). 1942;69(4):691-714. doi:10.1001/archinte.1942.00200160142011
Abstract

FUNCTIONAL ACTIVITY OF THE COMMON BILE DUCT AND THE SPHINCTER OF ODDI  The physiology of the biliary tract was reviewed in 1937.1 At that time the various factors chiefly affecting the flow of bile with especial reference to the secretory pressure of the liver, the contractility and storage function of the gallbladder, the resistance of the sphincter of Oddi and the effect of changes in duodenal tone and motility were discussed in some detail. The literature dealing with the sphincter mechanism of the common bile duct in human subjects has been comprehensively reviewed by Bergh.1a The recognition that the flow of bile through the various portions of the biliary tract is subject to physiologic control has had broad clinical implications, and an extensive clinical literature dealing with disturbances in this functional control has arisen in consequence. One of the most recent experimental analyses of the mechanics of the

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