[Skip to Navigation]
Article
October 1942

TREATMENT OF PNEUMONIA WITH SULFATHIAZOLE

Author Affiliations

DETROIT

From the Department of Medicine, Wayne University College of Medicine.

Arch Intern Med (Chic). 1942;70(4):558-566. doi:10.1001/archinte.1942.00200220048004
Abstract

Sulfathiazole (2-[paraaminobenzenesulfonamido]-thiazole) has been widely used for the treatment of pneumococcic pneumonia during the past two years. There are numerous reports attesting to its value, but only one series1 exceeding 250 cases has been described to date. The following report is based on 557 cases of pneumonia in which treatment was with sulfathiazole.

METHOD 

Diagnosis.  —The cases included in this study represent all patients over 12 years of age with pneumonia who were admitted to the pneumonia services of the City of Detroit Receiving Hospital and the William J. Seymour Hospital, Eloise, Mich., between Jan. 1, 1940 and Aug. 1, 1941 and who were treated with sulfathiazole. The diagnosis was confirmed by roentgenogram in every case. On admission sputum was typed directly by the Neufeld method, and the results were checked either by mouse inoculation or by the direct typing of a second specimen. Typing was repeated in the

×