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Article
January 1943

SUPERNORMAL CIRCULATION IN RESTING SUBJECTS (HYPERKINEMIA): WITH A STUDY OF THE RELATION OF KINEMIC ABNORMALITIES TO THE BASAL METABOLIC RATE

Author Affiliations

PHILADELPHIA

From the Research Department of Therapeutics, the William Pepper Laboratory of Clinical Medicine, and the Medical Division of the Hospital of the University of Pennsylvania.

Arch Intern Med (Chic). 1943;71(1):1-22. doi:10.1001/archinte.1943.00210010007001
Abstract

During the past fifteen years, estimations of basal, or resting, cardiac output, first by the ethyl iodide method and later by the ballistocardiogram, have been made for about 1,400 subjects. In this work we had both immediate and remote objectives in view. The first of the latter was attained when we secured 100 subjects with subnormal circulation and discussed the clinical significance of the abnormality.1 It has taken us three years longer to assemble data on 100 subjects with circulation above the normal, and a chief feature of this report is an account of this group.

In addition, using all our data, we have studied the relation between abnormalities of the amount of the resting circulation and of the basal metabolic rate.

By our studies important abnormalities have been demonstrated in many patients who have had symptoms referable to their circulation without detected organic disease. As these abnormalities seem

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