The mysterious association of fibroma of the ovary with hydrothorax has had infrequent notice in the literature of gynecology and none in that of internal medicine. The earliest recorded case seems to be that reported by Cullingworth1 in 1879. In 1906 Griffith and Williamson2 stated that "solid ovarian tumors are often accompanied by hydroperitoneum and sometimes by hydrothorax; this phenomenon has at present received no adequate explanation." In 1937 Meigs and Cass invited renewed attention to this syndrome. Again, in 1939, Meigs3 emphasized its importance, collecting 15 cases from the literature, 6 from a single hospital. This suggests that the condition is less rare than has been believed. As such cases fall in that no man's land between the internist and the specialist, the significance of the combined thoracic, abdominal and pelvic features may be disregarded. The result of this is too often the denial of life-preserving
HERRICK WW, TYSON TL, WATSON BP. ASSOCIATION OF HYDROTHORAX WITH OVARIAN FIBROMA (MEIGS'S SYNDROME). Arch Intern Med (Chic). 1943;71(3):370–376. doi:10.1001/archinte.1943.00210030071006
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