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Article
July 1943

BLOOD: A REVIEW OF THE RECENT LITERATURE

Author Affiliations

ANN ARBOR, MICH.

Arch Intern Med (Chic). 1943;72(1):115-145. doi:10.1001/archinte.1943.00210070123012
Abstract

APLASTIC ANEMIA AND REFRACTORY ANEMIAS  No new and important information concerning aplastic anemia was reported in 1942, with the possible exception that the condition may follow the use of sulfathiazole. A paper by Vaughan180 deals with 34 cases of aplastic anemia, both of the primary and of the secondary type. He quotes Rosenthal as stating that the disease may be defined as a progressive condition of unknown cause characterized by severe anemia, leukopenia, thrombopenia and marrow acellularity. When it does not conform to this description, it is regarded as atypical. The cases in which a cause for the disease can be ascertained are segregated as cases of the secondary type. Vaughan considers aplastic anemia in the broader sense, which includes the two subgroups indicated. Ten of the cases were of the secondary type; in 6 of these the anemia was due to arsphenamine, and in

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