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Article
September 1943

FRIEDLANDER'S BACILLUS SEPTICEMIA AND MENINGITIS: REPORT OF A CASE AND AUTOPSY, WITH AN ANALYSIS OF TWENTY-NINE CASES COLLECTED FROM THE LITERATURE

Author Affiliations

NASHVILLE, TENN.

From the Department of Medicine and the Department of Pathology, Vanderbilt University School of Medicine.

Arch Intern Med (Chic). 1943;72(3):319-328. doi:10.1001/archinte.1943.00210090020002
Abstract

Meningitis caused by Friedlünder's bacillus is a medical rarity. The case to be reported is of interest because of the scarcity with which reports of this disease have appeared in the American literature. It serves also to illustrate the danger of confusion with meningococcic meningitis. Until recently Friedlünder's bacillus meningitis was almost uniformly fatal, but in the last two years some cures have been obtained with sulfapyridine1 (2-[paraaminobenzenesulfonamido]-pyridine) as well as with sulfadiazine2 (2-[paraaminobenzenesulfonamido]-pyrimidine), which has become available subsequent to the occurrence of our case. It is hoped that in the future early diagnosis and vigorous use of the proper drug may make successful treatment more generally possible. Since it appears that the dawn of a new era in the therapy of this formidable disease is being witnessed, a consideration of 29 cases collected from the available literature is included as a background against which present developments may

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