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Article
September 1943

ACUTE BRUCELLOSISCLINICAL, BACTERIOLOGIC AND SEROLOGIC STUDIES OF THREE PATIENTS

Arch Intern Med (Chic). 1943;72(3):346-352. doi:10.1001/archinte.1943.00210090047004
Abstract

Perusal of the large number of case reports of undulant fever contained in the literature is unsatisfactory not only because of frequent justifiable doubt as to the correctness of the diagnosis but because of the paucity of bacteriologic and serologic studies. Recently 3 patients suffering from undulant fever have afforded an excellent opportunity for study of the persistence of bacteremia and the behavior of demonstrable serum antibodies for Brucella throughout the course of the illness. The technics used for blood cultures and for the serologic tests have been described elsewhere.1 All 3 patients came under observation during the first month of illness, and all received treatment with sulfonamide drugs, the results of which will be discussed.

REPORT OF CASES 

Case 1.  —C. M., a 35 year old white man, a salesman, entered the hospital on Jan. 13, 1941, complaining of chills and fever of three weeks' duration. The familial,

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