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December 1943


Author Affiliations


From the department of Neuropsychiatry, Harvard University, and the Department of Psychiatry, Massachusetts General Hospital.

Arch Intern Med (Chic). 1943;72(6):795-806. doi:10.1001/archinte.1943.00210120089009

MOTONEURON  At the termination of every reflex arc we find a final neurone, the ultimate conductive link to an effector organ, gland, or muscle. This last link in the chain—e. g., the motoneurone-differs obviously in one important respect from the first link in the chain. It does not subserve exclusively impulses generated at one single receptive source alone, but receives impulses from many receptive sources situate in many and various regions of the body.Thus in 1904 Sherrington1 described the "final common path" of nervous impulses from anterior horn cell in the spinal cord to motor end plate in the striated muscle. On his work depends most of the knowledge of the reflex function of cord and muscle, and recent work is largely elaboration of what he began. During the last two years several important discoveries have been made in this field.In the first place, Elliott2 has

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