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Article
November 1944

EFFECT OF SULFONAMIDE COMPOUNDS ON TRANSIENT BACTEREMIA FOLLOWING EXTRACTION OF TEETHI. SULFANILAMIDE

Arch Intern Med (Chic). 1944;74(5):346-353. doi:10.1001/archinte.1944.00210230038003
Abstract

Bacteremia has long been known to follow almost all surgical procedures, from curettage of the uterus1 and operations on the urethra2 to abdominal operations such as simple appendectomy.3 In 1932 Richards4 reported the occurrence of bacteremia following irritation of foci of infection, such as joints, tonsils, prostates, furuncles and gums. Bacteremia following extraction of teeth has been reported by numerous investigators.5 It remained for Okell and Elliott5a to demonstrate that bacteremia follows extraction of teeth more frequently than had hitherto been realized. Of cultures of blood taken immediately after dental extraction in 138 cases, 60.9 per cent revealed bacteria. In 1939 Elliott,5f using an improved technic and selected patients, was able to obtain positive results from 86 per cent of cultures in 21 cases.

One of the more unusual features in the work of Okell and Elliott5a was that of 110 persons undergoing extraction 10.9 per cent were

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