"Correction charts" by which the observed values for the sedimentation rate are supposed to be corrected are used in many hospitals and by many practitioners in the United States. The scientific background of these correction charts is rather dubious. I began to check this scientific background after observing some instances in which in spite of a correct technic and a correct use of the correction chart the value calculated for the sedimentation rate was "negative." When I asked workers in laboratories in New York, Chicago and San Francisco about their experience in this respect, the reply was that several of them also remembered cases in which the value for the sedimentation rate was found to be "negative" after "correction" with a correction chart. Osgood1 likewise observed such results. At my request Dr. E. Moss put at my disposal the reports of the determinations of the sedimentation rate made in
PETERS JT. DETERMINATION OF SEDIMENTATION RATE OF RED BLOOD CELLS: USE OF SO-CALLED CORRECTION CHARTS AND OPTIMUM LENGTH AND DIAMETER OF THE PIPET. Arch Intern Med (Chic). 1945;75(2):105–108. doi:10.1001/archinte.1945.00210260033004
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