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September 1945


Author Affiliations


From the Peripheral Vascular Section of the Edward B. Robinette Foundation, Medical Clinic, Hospital of the University of Pennsylvania.

From the Arthritis Clinic, Medical Clinic, Hospital of the University of Pennsylvania.

Arch Intern Med (Chic). 1945;76(3):139-142. doi:10.1001/archinte.1945.00210330010002

During the grading of the basal vascular tone1 of normal persons and patients with various diseases by a method recently described by two of us,2 it was found that patients with rheumatoid arthritis had a characteristic basal vascular tone which explained certain clinical features of the disease. In some patients the diagnosis of rheumatoid arthritis first suggested itself by a characteristic vascular behavior, a dissociated response between the affected and the unaffected digits not ordinarily seen where there is no arterial occlusion.

Since there was no objective information as to the grade of tone in the peripheral vessels of patients with rheumatoid arthritis, the vascular responses of a group of such patients were studied by the method described in this paper. It is significant that in all the patients with rheumatoid arthritis subsequently studied there was a consistently high grade of basal vascular tone in contrast to that