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March 1946

SYPHILIS: A Review of the Recent Literature

Author Affiliations


From the United States Public Health Service and the Johns Hopkins University Venereal Disease Research and Postgraduate Training Center.

Arch Intern Med (Chic). 1946;77(3):332-364. doi:10.1001/archinte.1946.00210380097007

THE material for this article has been selected from publications which have appeared from July 1944 to June 1945. In this review1 especial emphasis is placed on subjects of particular current importance, e. g., biologic false positive reactions to serologic tests for syphilis and new methods of treatment, especially with penicillin, though articles on other important subjects are not neglected. The number of European journals available for review is negligible.

EXPERIMENTAL SYPHILIS  Chesney and Woods2 report experiments to determine the extent to which a primary syphilitic infection of the cornea in rabbits is followed by the development of a local corneal immunity, by the generalized spread of Treponema pallidum and by the development of a general immunity to the infection. Female rabbits were inoculated intracorneally with a virulent strain of T. pallidum, and the disease was allowed to run its course until the lesions which had developed at the site