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Article
July 1946

ALLERGYA Review of the Literature of 1944 and 1945, with Comments on Future Problems

Arch Intern Med (Chic). 1946;78(1):108-122. doi:10.1001/archinte.1946.00220010118008
Abstract

HAY FEVER  There are two parts to the treatment of hay fever. One concerns the choice of the particular extract to be used in treatment; the other concerns the technic of doses.The choice of extracts is important, and, as usual, it is the history which gives the best clue. Skin tests are always interesting, but when one can demonstrate many skin tests with positive reactions that have no symptoms to go with them and then can find clinical evidence of sensitiveness in spite of skin tests with negative reactions one learns to recognize the limitations of the method.Around Boston, for example, one can distinguish two varieties of what used to be called the typical ragweed history. In one group of patients, the symptoms of hay fever begin around the middle of August, the peak of symptoms is near the first of September and then

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