[Skip to Content]
[Skip to Content Landing]
Article
September 1946

TREATMENT OF GUMMATOUS HEPATIC SYPHILIS WITH PENICILLINReport of Two Cases

Arch Intern Med (Chic). 1946;78(3):313-322. doi:10.1001/archinte.1946.00220030060004
Abstract

THIS is the first report dealing with penicillin as used in the treatment of gummatous hepatic syphilis. Two cases are presented.

REPORT OF CASES 

Case 1.  —A 49 year old Negro housewife was admitted to the hospital on Oct. 25, 1943, because of right-sided abdominal and thoracic discomfort of four years' duration and soreness of the right knee of two years' duration. The past and family histories were not pertinent except that a blood serologic test for syphilis had been negative in 1929. The patient said that she had contracted no venereal diseases.For four years she had had attacks of "pleurisy" on the right side, which had at times required medical care. One and a half years before admission she began to be troubled with pain and "tightness" in the right upper quadrant of the abdomen, together with a feeling of fulness in the region of the liver.

×