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September 1946

GASTROENTEROLOGYA Review of the Literature from July 1944 to June 1945

Arch Intern Med (Chic). 1946;78(3):323-366. doi:10.1001/archinte.1946.00220030070005


Congenital Anomalies.  —Sumner and Morris217 report a case in which duodenal atresia in a newborn infant, diagnosed early, was successfully treated by duodenojejunostomy. In Mosquera's218 case the atresia proved fatal at the age of 18 months.

Secretion.  —Comfort219 reviews the literature of the last thirty years on duodenal content in health and disease and reaches the following conclusions: During fasting the duodenal content of healthy subjects with achlorhydria is alkaline; in those with acid-secreting stomachs it is acid both in the fasting state and after meals; the reaction of the duodenal content of healthy subjects varies roughly with the amount of acid entering the duodenum; the acidity does not vary greatly between the first and the second portion; drugs, such as atropine sulfate, morphine and the sodium salt of dehydrocholic acid, increase the average pH of the duodenal content; the antacids