SINCE aerobic types of Actinomyces may be highly pathogenic to man and are not so well known as the anaerobic Actinomyces bovis, the death of 2 patients infected with an aerobic variety appears worthy of record, not only because of the rarity of the organism, but also to emphasize the necessity of accurate diagnosis and vigorous therapy.
In 1891, Eppinger1 reported the finding of an aerobic gram-positive, acid-fast actinomyces in cerebral abscesses and meningeal exudate of a man who became delirious and died in two weeks. This organism readily grew on ordinary mediums as small starlike colonies, due to the radiating filaments, and was named Cladothrix asteroides. It has since been known as Streptothrix eppingeri, Streptothrix asteroides, Oospora asteroides and Actinomyces asteroides, and is now called Nocardia asteroides.2
In 1921, Henrici and Gardner3 were able to collect but 26 reported cases of infections with aerobic acid-fast Actinomyces, and the causative
KIRBY WMM, McNAUGHT JB. ACTINOMYCOSIS DUE TO NOCARDIA ASTEROIDES: Report of Two Cases. Arch Intern Med (Chic). 1946;78(5):578–591. doi:10.1001/archinte.1946.00220050085005
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: